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Testing Status of Dimethylethanolamine (DMAE) M200084

 

CASRN: 108-01-0

Formula: C4-H11-N-O

Synonyms/Common Names

  • Deanol
  • Dimethylaminoethanol
  • DMAE
  • Ethanolamine
  • Ethanol, 2-(dimethylamino)-
  • N,N-Dimethylethanolamine

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage)  (K20084)  Completed 
    • Citation: Disposition of DMAE and Choline in Rats and Mice after Oral and Intravenous Administration. Lovelace Biomedical and Environmental Research Institute. July 23, 2012
    • Male and Female Rats: Wistar Han; Male and Female Mice: B6C3F1
    • Dose: 10, 100, 500 mg/kg.

Genetic Toxicology

  • Drosophila  (345686)  Completed 
    • Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
    • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
  • Salmonella  (990909)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Equivocal 
  • Salmonella  (994377)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative