National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m20134

Testing Status of Ergotamine tartrate - M20134

 

CASRN: 379-79-3

Related: ERGOTAMINE (CAS 113-15-5)

Formula: C33-H35-N5-O5.1/2C4-H6-O6

Synonyms/Common Names

  • Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (2:1) (salt)

Known Uses

Used in the treatment of migraine headaches, naturally occurring in rye fungus

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (793132)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 
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