National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m20144

Testing Status of Doxylamine succinate - M20144

 

CASRN: 562-10-7

Formula: C17-H22-N2-O.C4-H6-O4

Synonyms/Common Names

  • Butanedioic acid, compd. with N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine (1:1)

Known Uses

Antihistamine closely related to diphenhydramine

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (968948)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Salmonella  (057585)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 
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