National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m20186

Testing Status of Amphotericin B - M20186

 

CASRN: 1397-89-3

Formula: C47-H73-N-O17

Synonyms/Common Names

  • Anfotericine B

Known Uses

Antifungal obtained from streptomycetes (Merck 1989)

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (995618)  Completed 
    • Citation: Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Salmonella  (633898)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Negative 
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