Testing Status of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate M20247
CASRN: 6197-30-4
Formula: C24-H27-N-O2
Synonyms/Common Names
- Octocrylene
- 2-Propenoic acid, 2-cyano-3,3-diphenyl-, 2-ethylhexyl ester (9CI)
Known Uses
Sunscreen. UV stabilizer.
Chemical Properties
Toxicity Effects (HSDB)
Special Studies
- 3 days Hershberger Assay (Gavage)
(K20247B)
Completed
- Citation: Final Report: The Hershberger Bioassay; Oxybenzone, Octylmethoxycinnamate, Octylsalate, Octocrylene. 04 January 2012
- Male Rats: Harlan Sprague-Dawley
- Dose: 20, 64, or 200 mg/ml.
- 3 days Uterotrophic Assay (Gavage)
(K20247)
Completed
- Citation: Final Report. The Uterotrophic Assay with Oxybenzone, Octylmethoxycinnamate, Octylsalate and Octocrylene. 01 September 2011 Revised: 20 April 2012
- Female Rats: Harlan Sprague-Dawley
- Dose: 5 mL/kg.
Genetic Toxicology
- Salmonella
(066654)
Completed
- Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
- Negative
in vitro Testing
- Androgen Receptor Binding Assay
(V20247B)
Completed
- Androgen Receptor Binding Assay
- Estrogen Receptor Binding Assay
(V20247C)
Completed
- Estrogen Receptor Binding Assay
- H295R Steroidogenesis Assay
(V20247)
Completed
- H295R Steroidogenesis Assay
- Androgen Receptor Transactivation Assay
(V20247D)
Completed
- Androgen Receptor Transactivation Assay
- Estrogen Receptor Transactivation Assay
(V20247E)
Completed
- Estrogen Receptor Transactivation Assay
- Human Recombinant Aromatase Assay
(V20247G)
Completed
- Human Recombinant Aromatase Assay