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Testing Status of Isodecyl Diphenyl Phosphate M20299

 

CASRN: 29761-21-5

Formula: C22-H31-O4-P

Synonyms/Common Names

  • Flame Retardant 1
  • IDDP
  • Phosphoric acid, isodecyl diphenyl ester (9CI)

Known Uses

Plasticizer for biodegradable tampon ejectors

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 5 days (Gavage)  (C20299)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 0.169, 0.338, 0.675, 1.35, 2.70 mMol/kg; 5/species/dose.

Special Studies

  • C. elegans  (W20299)  Completed 
    • Citation: Behl M, Rice JR, Smith MV, Co CA, Bridge M, Hsieh JH, Freedman JH, Boyd WA. Comparative toxicity of organophosphate flame retardants and polybrominated diphenyl ethers to c. Elegans. Toxicol Sci. 2016 Aug;154(2):241-252Pubmed Abstract
    • C. elegans
    • Dose: Growth: 0, 0.4, 0.63, 1, 1.6, 2.5, 4.0, 6.3, 10, 16, 25, 40, 63, 100, 160, 250, 400, 630, 1000uMRepro: 0, 0.5, 1, 2, 4, 8, 16, 32, 63, 125, 250, 500uMFeeding: 0, 10, 16, 25, 40, 63, 100, 160, 250, 400, 630, 1000uM.

Genetic Toxicology

  • Salmonella  (083218)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 

Toxicogenomics

  • Microarray Analysis (Gavage)  (T20299)  Completed 
    • Rats: Harlan Sprague-Dawley