National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m20327

Testing Status of Atrazine - M20327

 

CASRN: 1912-24-9

Related: CASRNs 38641-94-0, 58-90-2, 2212-67-1

Formula: C8-H14-Cl-N5

Synonyms/Common Names

  • AATREX
  • 1,3,5-Triazine-2,4-diamine, 6-chloro-N-ethyl-N'-(1-methylethyl)-

Known Uses

Herbicide, pesticide

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Genetic Toxicology

  • Salmonella  (497043)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Negative 

Organ Systems Toxicity

  • Immunotoxicity (Gavage)  (IMM92045)  Completed 
    • Mice: B6C3F1
    • Dose: 0, 25, 250, 500 MG/KG.
  • 14 days Immunotoxicity (Gavage)  (IMM94002)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 25, 250, 500 MG/KG.
  • 14 days Immunotoxicity (Gavage)  (IMM94003)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 25, 50, 100, 250, 500 MG/KG.
  • 4 days, 8 days Immunotoxicity (Topical Application)  (IMM95006)  Completed 
    • Female Mice: B6C3F1
    • Dose: 10, 20, AND 30% IN ACETONE (99.8%) FOR SENSITIZATION AND 30% FOR CHALLENGE; 0.25% DNFB AS POSITIVE CONTROL CONTROL AND 0.5% FOR CHALLENGE.
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