National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m20409

Testing Status of Verapamil - M20409

 

CASRN: 52-53-9

Formula: C27-H38-N2-O4

Synonyms/Common Names

  • Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-(9CI)

Known Uses

Vasodilator, cardiac depressant, anti-arrhythmic agent

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Mechanisms  (S0463)  Completed 
    • Citation: Ghanayem BI, Matthews HB, Maronpot RR. Calcium channel blockers protect against ethanol- and indomethacin-induced gastric lesions in rats. Gastroenterology. 1987 Jan;92(1):106-11.Pubmed Abstract
    • Male Rats: F344/N
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