National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m20422

Testing Status of 1,2,3,4,6,7-Hexabromonaphthalene - M20422

 

CASRN: 75625-24-0

Formula: C10-H2-Br6

Synonyms/Common Names

  • Naphthalene, 1,2,3,4,6,7-hexabromo-

Known Uses

Hexabromonaphthalene (HBN) has been identified as a toxic contaminant of a mixture of polybrominated biphenyls (PBBs) that is used commercially as a fire retardant.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage; Intravenous)  (S0256)  Completed 
    • Citation: Birnbaum LS, Darcey DJ, McKinney JD. Hexabromonaphthalene contaminants of polybrominated biphenyls: chemical composition and disposition in the rat. J Toxicol Environ Health. 1983 Oct-Dec;12(4-6):555-73.Pubmed Abstract
    • Rats
  • Mechanisms (Gavage)  (S0481)  Completed 
    • Citation: Miller CP, Birnbaum LS. Teratologic evaluation of hexabrominated naphthalenes in C57BL/6N mice. Fundam Appl Toxicol. 1986 Oct;7(3):398-405.Pubmed Abstract
    • Female Mice: C57BL/6
    • Dose: 1.0, 2.5, 5.0, 7.5 & 10.0 MG HBN/KG.
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