National Toxicology Program

National Toxicology Program

Testing Status of Cobalt sulfate heptahydrate - M88032


CASRN: 10026-24-1


Formula: Co-O4-S.7H2-O

Synonyms/Common Names

  • Cobaltous sulfate
  • Sulfuric acid, cobalt(2+) salt (1:1), heptahydrate

Known Uses

Drying agent for varnishes and inks; component of electroplating solutions

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Inhalation)  (C61530)  Completed 
    • Mice: B6C3F1
  • 3 weeks (Inhalation)  (C61530)  Completed 
    • Rats: F344/N
  • 13 weeks (Inhalation)  (C61530)  Report Complete 
    • TOX-05 (NIH Number: 91-3124)
      Toxicity Studies of Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1 Mice (Inhalation Studies) (CASRN 10026-24-1)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M:0, .3, 1.0, 3.0, 10.0, 30.0 MG/M3.

Long-Term Carcinogenicity

  • 2 years (Inhalation)  (C61530B)  Report Complete 
    • TR-471 (NIH Number: 98-3961)  (Peer Review Approval 12/11/1996A )
      Toxicology and Carcinogenesis Studies of Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Some Evidence 
      • Female Rats Clear Evidence 
      • Male Mice Clear Evidence 
      • Female Mice Clear Evidence 
    • Dose: R&M: 0, 0.3, 1.0, OR 3.0 MG/M3; 50/SEX/SPECIES/GROUP.

Genetic Toxicology

  • Salmonella  (591193)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Weakly Positive 
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