National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m88073

Testing Status of Propylene glycol monomethyl ether, alpha - M88073

 

CASRN: 107-98-2

Formula: C4-H10-O2

Synonyms/Common Names

  • PGME
  • 2-Propanol, 1-methoxy- (8CI)(9CI)

Known Uses

Solvent in lacquer and paint formulations; in printing ink formulations; in a variety of industrial and household cleaners; in antifreeze; solvent in pesticide formulations. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage)  (S0240)  Completed 
    • Male and Female Rats: F344/N; Male and Female Mice

Organ Systems Toxicity

  • 120 day minimum Continuous Breeding (Legacy) (Dosed-Water)  (RACB85069)  Completed 
    • Citation: Propylene Glycol Monomethyl Ether: Reproduction and Fertility Assessment in CD-1 Mice When Administered in Drinking Water
    • Male and Female Mice: Swiss
    • Dose: N/A; 0, .5, 1, 2%; N/A; N/A.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.