National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m88085

Testing Status of 2-Methoxyethyl acetate - M88085

 

CASRN: 110-49-6

Formula: C5-H10-O3

Synonyms/Common Names

  • Ethanol, 2-methoxy-, acetate (9CI)
  • Ethylene glycol monomethyl ether acetate
  • 2-MEA

Known Uses

50% consumption as chemical intermediate (e.g. In plasticizer manufacture). 50% consumption in specialty solvent applications, inks and photo resist formulations. (EPA)

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage)  (S0525)  Completed 
    • Rats

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (216435)  Completed 
    • Citation: Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Salmonella  (327882)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Equivocal 
  • Salmonella  (655694)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Weakly Positive 

Organ Systems Toxicity

  • 7 to 14 GD Short-Term in vivo Repro. Tox. (Gavage)  (T0066)  Completed 
    • Citation: Screening of Priority Chemicals for Reproductive Hazards
    • Female Mice: M
    • Dose: 1225 MG/KG BODY WEIGHT.
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