National Toxicology Program

National Toxicology Program

Testing Status of Rhein (1,8-dihydroxy-3-carboxyl anthraquinone) - M88241


CASRN: 478-43-3

Formula: C15-H8-O6

Synonyms/Common Names

  • 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid

Known Uses

Plant-derived anthraquinone laxative

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • C. elegans  (W88241)  Completed 
    • C. elegans
    • Dose: 100, 75, 50 uM.

Genetic Toxicology

  • Salmonella  (849805)  Completed 
    •  Positive 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.