Testing Status of Dichloroacetic acid M882484

 

CASRN: 79-43-6

Formula: C2-H2-Cl2-O2

Synonyms/Common Names

  • Bichloracetic acid
  • DCA
  • Dichloracetic acid
  • Dichloroethanoic acid

Known Uses

Breakdown product of drinking water disinfectants, astringent, use in treatment of lactic acidosis, keratolytic agent (Merck 1989). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • (K07379)  Completed 

    Genetic Toxicology

    • Micronucleus  (A15985)  Completed 
      • Mice: Tg.AC (FVB/N) Hemizygous
      • Male Negative 
      • Female Negative 
    • Micronucleus  (A67778)  Completed 
      • Mice: B6C3F1
      • Male Negative 
      • Female Positive 
    • Micronucleus  (A72842)  Completed 
      • Mice: Tg.AC (FVB/N) Hemizygous
      • Male Negative 
      • Female Negative 
    • Micronucleus  (A91472)  Completed 
      • Mice: P53 +/- (C57BL/6)
      • Male Negative 
      • Female Negative 
    • Salmonella  (024933)  Completed 
      •  Positive 
    • Salmonella  (A67820)  Completed 
      •  Positive 

    Organ Systems Toxicity

    • less than or equal to 28 days Spermiation Inhibition (Gavage)  (RACB93158)  Completed 
      • Male Rats: F344/N
      • Dose: </= 125 MG/KG.