Testing Status of Interferon A (AIDS Initiative) M890008

 

CASRN: 76543-88-9

Formula: C860-H1353-N227-O255-S9

Synonyms/Common Names

  • Interferon alfa-2a
  • Roferon-A

Known Uses

Experimental AIDS therapy, antiviral drug, antineoplastic agent

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 4 weeks (Subcutaneous Injection)  (C89001)  Completed 
    • Mice: B6C3F1
    • Dose: MICE ONLY: 500000 UNITS/ANIMAL.

Long-Term Carcinogenicity

  • 2 years (Subcutaneous Injection)  (C89001)  Report Complete 
    • TR-469 (NIH Number: 99-3959)  (Peer Review Approval 12/11/1996A )
      Toxicology and Carcinogenesis Studies of AZT (CASRN 30516-87-1) and AZT/ a-Interferon A/D B6C3F1 Mice (Gavage Studies)
    • Mice: B6C3F1
    • Dose: 5000 UNITS 3X A WEEK; 50/SEX/GROUP.