National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m90018

Testing Status of Phosphine - M90018

 

CASRN: 7803-51-2

Formula: H3-P

Synonyms/Common Names

  • Hydrogen phosphide
  • Phosphorus trihydride

Known Uses

Insecticide used for fumigating animal feed, leaf stored tobacco, box cars, rodent control, formed in putrefaction of organic materials containing phosphate (Merck 1989); doping agent for n-type semiconductors; polymerization condensation catalyst [s

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Inhalation)  (C89022)  Completed 
    • Rats: F344/N; Mice: B6C3F1

Genetic Toxicology

  • Micronucleus  (A97950)  Completed 
    • Citation: Kligerman, A.D., Bishop, J.B., Erexson, G.L., Price, H.C., O'Connor, R.W., Morgan, D.L. Cytogenetic and germ cell effects of phosphine inhalation by rodents. II. Subacute exposures to rats and mice. Environ. Molec. Mutagen. Vol. 24 (4) (1994) 301-6
    • Mice: B6C3F1
    • Male Negative (Nonstandard Protocol) 
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