National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m90024

Testing Status of Interferon AD + ddC (AIDS Initiative) - M90024

 

CASRN: INTDDCCOMB

Formula: + C9-H13-N3-O3

Synonyms/Common Names

  • Interferon AD + Dideoxycytidine

Secondary:

  • 7481-89-2 - 2',3'-Dideoxycytidine
  • INTERFERONAD - Interferon AD (AIDS Initiative)

Known Uses

Experimental drug used for AIDS therapy.

Short-Term Toxicity

  • 4 weeks (Subcutaneous Injection)  (C89030)  Completed 
    • Mice: B6C3F1
    • Dose: MICE ONLY - DUAL ROUTES: IFN/AD (SC/IJ): 500, 5000, 50000, OR 500000 UNITS/MOUSE/DAY: DDC (GAVAGE): 0, 250, OR 1000 MG/KG.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.