National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m90061

Testing Status of 5-Aminosalicylic acid - M90061

 

CASRN: 89-57-6

Formula: C7-H7-N-O3

Synonyms/Common Names

  • Mesalazine

Known Uses

Used in the treatment of ulcerative colitis and Crohns disease

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (040238)  Completed 
    • Citation: Witt, K.L., Bishop, J.B., McFee, A.F., Kumarroo, V. Induction of chromosomal damage in mammalian cells in vitro and in vivo by Sulfapyridine or 5-aminosalicylic acid. Mutation Res. Vol. 283 (1992) 59-64
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Micronucleus  (805434)  Completed 
    • Mice: B6C3F1
    • Male Negative 
  • Salmonella  (759488)  Completed 
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.