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Testing Status of Sulfapyridine M90065

 

CASRN: 144-83-2

Formula: C11-H11-N3-O2-S

Synonyms/Common Names

  • Benzenesulfonamide, 4-amino-N-(2-pyridinyl)- (9CI)

Known Uses

Used in the treatment of dermatitis

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Chromosome Aberrations  (673616)  Completed 
    • Mice
    •  Negative (Nonstandard Protocol) 
  • Chromosome Aberrations  (A49990)  Completed 
    • Mice
    •  Negative (Nonstandard Protocol) 
  • In Vitro Cytogenetics (CA/SCE)  (788992)  Completed 
    • Citation: Witt, K.L., Bishop, J.B., McFee, A.F., Kumarroo, V. Induction of chromosomal damage in mammalian cells in vitro and in vivo by Sulfapyridine or 5-aminosalicylic acid. Mutation Res. Vol. 283 (1992) 59-64
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Micronucleus  (163220)  Completed 
    • Mice: B6C3F1
    • Male Positive (Nonstandard Protocol) 
  • Micronucleus  (673616)  Completed 
    • Mice: B6C3F1
    • Male Not a Valid Test 
  • Micronucleus  (711865)  Completed 
    • Citation: Witt, K.L., Bishop, J.B., McFee, A.F., Kumarroo, V. Induction of chromosomal damage in mammalian cells in vitro and in vivo by Sulfapyridine or 5-aminosalicylic acid. Mutation Res. Vol. 283 (1992) 59-64
    • Rats: Fischer 344
    • Male Equivocal 
  • Micronucleus  (A49990)  Completed 
    • Mice: B6C3F1
    • Male Positive 
    • Female Positive 
  • Micronucleus  (A80525)  Completed 
    • Mice: B6C3F1
    • Male Positive 
  • Salmonella  (635845)  Completed 
    •  Negative 
  • Sister Chromatid Exchanges  (673616)  Completed 
    • Mice
    • Sister Chromatid  Positive (Nonstandard Protocol)