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Testing Status of Chlorinated water M910004



Synonyms/Common Names

  • Chlorine/Sodium hypochlorite
  • Chlorine/Sodium hypochlorite


  • 7782-50-5 - Chlorine
  • 7681-52-9 - Hypochlorous acid, sodium salt

Known Uses

Chemicals used in the chlorination and chloramination of drinking water. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Long-Term Carcinogenicity

  • 2 years (Dosed-Water)  (C91004)  Completed 
    • TR-392 (NIH Number: 92-2847)  (Peer Review Approval 11/19/1990A )
      Toxicology and Carcinogenesis Studies of Chlorinated Water (CASRNs 7782-50-5 and 7681-52-9) and Chloraminated Water (CASRN 10599-90-3) (Deionized and Charcoal-Filtered) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats No Evidence 
      • Female Rats Equivocal Evidence 
      • Male Mice No Evidence 
      • Female Mice No Evidence 
    • Dose: R&M: 0, 70, 140, 275 PPM/70 PER GROUP.