National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m910061

Testing Status of 2,6-Dinitrotoluene - M910061

 

CASRN: 606-20-2

Formula: C7-H6-N2-O4

Synonyms/Common Names

  • 2-Methyl-1,3-dinitrobenzene

Known Uses

Chemical intermediate for toluene-2,60diamine, a toluene diisocyanate intermediate; gelatinizing & waterproofing agent in explosives; used in the synthesis of TNT, urethane polymers, flexible and rigid foams, surface coatings and dyes. (HSDB 1991)

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Metabolism (Dosed-Water)  (S0693)  Completed 
    • Citation: Chapman DE, Michener SR, Powis G. Metabolism of 2,6-dinitro[3-3H]toluene by human and rat liver microsomal and cytosolic fractions. Xenobiotica. 1992 Aug;22(8):1015-28.Pubmed Abstract
    • Rats: Harlan Sprague-Dawley; Human (Cell Lines)

Genetic Toxicology

  • Salmonella  (A94801)  Completed 
    •  Positive 
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