National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m910077

Testing Status of Polysorbate 20 - M910077

 

CASRN: 9005-64-5

Formula: C26-H50-O10 (mixture)

Synonyms/Common Names

  • Polyoxyethylene sorbitan monolaurate
  • Tween 20

Known Uses

Emulsifier & dispersing agent for medicinal products, defoamer in foods

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • C. elegans  (W91077)  Completed 
    • C. elegans
    • Dose: Growth:0, 0.001, 0.0016, 0.0025, 0.004, 0.0063, 0.01, 0.016, 0.025, 0.04, 0.063, 0.1%.

Organ Systems Toxicity

  • Conventional Teratology (Gavage)  (TER91010)  Completed 
    • Citation: Final Report on the Developmental Toxicity of Polyoxyethylene Sorbitan Monolaurate in Sprague-Dawley Rats
    • Rats: Sprague Dawley
    • Rats Maternal Negative 
    • Rats Fetal Negative 
    • Dose: 0, 500, 5000 MG/KG/DAY.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.