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Testing Status of Lead ores M920001

 

CASRN: LEADORES

Synonyms/Common Names

  • Black Cloud Mine Ore (Colorado)
  • Red Dog Mine Ore (Alaska)
  • West Fork Mine Ore (Missouri)

Known Uses

Lead ores from various geographical locations

Short-Term Toxicity

  • 13 & 26 weeks (Dosed-Feed)  (C92001)  Completed 
    • Rats: F344/N
    • Dose: ORES: MALE RATS, 30/GROUP; PB SULFIDE USED AS STANDARD: MALE AND FEMALE 30/GROUP; 10 ADD'L MALES TREATED 180 DAYS (PB SULFIDE) 0, 10, 30, & 100 PPM; PARTICLE SIZE <38 MICRONS; 30, 60, 90-DAY SACRIFICE.

Special Studies

  • Absorption Disposition Metabolism Elimination (Dosed-Feed)  (S0375)  Completed 
    • Male Rats: F344/N
    • Dose: 10, 30, 100 PPM.
  • Absorption Disposition Metabolism Elimination (Dosed-Feed)  (S0478)  Completed 
    • Citation: Dieter MP, Matthews HB, Jeffcoat RA, Moseman RF. Comparison of lead bioavailability in F344 rats fed lead acetate, lead oxide, lead sulfide, or lead ore concentrate from Skagway, Alaska. J Toxicol Environ Health. 1993 May;39(1):79-93.Pubmed Abstract
    • Male Rats: F344/N
    • Dose: 0, 10, 30 OR 100 PPM.