Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Fumonisin B1 M920002


CASRN: 116355-83-0

Formula: C34-H59-N-O15

Synonyms/Common Names

  • 1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-4,9,11-trihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester

Known Uses

Mycotoxin produced by certain strains of fusarium moniliforme, a commonly occurring fungi on U.S. agricultural products, especially corn. No known uses

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 4 weeks (Dosed-Feed)  (C92002B)  Completed 
    • Rats: F344/N; Mice: B6C3F1/NCTR BR (C57BL/6N x C3H/HEN MTV-)
    • Dose: R&M: 100, 175, 250, or 500 ppm.
  • 13 weeks (Dosed-Feed)  (C92002)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 1, 3, 9, 27, or 81 ppm; 15/sex/species/group.

Long-Term Carcinogenicity

  • 2 years (Dosed-Feed)  (C92002B)  Completed 
    • TR-496 (NIH Number: 01-3955)  (Peer Review Approval 05/21/1999A )
      Toxicology and Carcinogenesis Studies of Fumonisin B1 (CASRN 116355-83-0) in F344/N Rats and B6C3F1 Mice (Feed Studies)
    • Rats: F344/N; Mice: B6C3F1/NCTR BR (C57BL/6N x C3H/HEN MTV-)
    • Carcinogenesis Results
      • Male Rats Clear Evidence 
      • Female Rats No Evidence 
      • Male Mice No Evidence 
      • Female Mice Clear Evidence 
    • Dose: R&M: 0, 5, 15, 50, 100, or 150 ppm.

Special Studies

  • C. elegans  (S0952)  Completed 
    • C. elegans

Organ Systems Toxicity

  • 3 to 19 GD Conventional Teratology (Gavage)  (TER94002)  Completed 
    • Female Rabbit: New Zealand White
    • Dose: 0.25, 0.50, 1.25, OR 1.75 MG/KG -- DOSE FINDING STUDY.