National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m920015

Testing Status of Fluconazole - M920015

 

CASRN: 86386-73-4

Formula: C13-H12-F2-N6-O

Synonyms/Common Names

  • alpha-(2,4-Difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol (9CI)
  • Triazole

Known Uses

Triazole antifungal agent which is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • 5 days -- challenged 7 days later with 10% solution Immunotoxicity (Topical Application & Subcutaneous Injection)  (IMM91024)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 1, 3, 10%.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.