Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Ethyl vinyl ketone M920019

 

CASRN: 1629-58-9

Formula: C5-H8-O

Synonyms/Common Names

  • EVK
  • 1-Penten-3-one
  • Propionylethylene
  • Vinyl ethyl ketone

Known Uses

Natural& synthetic flavoring substance in orange aqueous essence & oils for flavoring & aroma enhancement, especially of orange juice. Reagent/chemical intermediate in organic synthesis; starting materials to produce pharmaceutical intermediates. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Inhalation)  (C92006)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 4, 8 OR 16 PPM.
  • 13 weeks (Inhalation)  (C92006)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 2, 4, OR 8 PPM.

Genetic Toxicology

  • Micronucleus  (A17802)  Completed 
    • Mice: B6C3F1
    • Male Negative 
  • Micronucleus  (A40627)  Completed 
    • Rats: Fischer 344
    • Male Negative 
  • Micronucleus  (A65262)  Completed 
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative 
  • Salmonella  (A91243)  Completed 
    •  Positive