National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m920020

Testing Status of 2-Cyclohexen-1-one - M920020

 

CASRN: 930-68-7

Formula: C6-H8-O

Synonyms/Common Names

  • CHO
  • 1-Cyclohexen-3-one
  • 2-Cyclohexenone

Known Uses

Industrial chemical intermediate with numerous applications in chemical process industry including use as pharmaceutical intermediate and agricultural chemical intermediate; widely used as reagent; antifungal agent/mold inhibitor for bread. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Short-Term Toxicity

  • 2 weeks (Inhalation)  (C92007)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 2.5, 5, OR 10 PPM.
  • 13 weeks (Inhalation)  (C92007)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 2.5, 5, OR 10 PPM.

Genetic Toxicology

  • Micronucleus  (A07473)  Completed 
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative 
  • Micronucleus  (A12841)  Completed 
    • Rats: Fischer 344
    • Male Negative 
  • Salmonella  (A33655)  Completed 
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.