National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m930031

Testing Status of Allyl acetate - M930031

 

CASRN: 591-87-7

Related: ALLYL ALCOHOL (107-18-6)

Formula: C5-H8-O2

Synonyms/Common Names

  • Acetic acid, allyl ester
  • Acetic acid, 2-propenyl ester
  • 3-Acetoxypropene
  • 3-Acetoxy-1-propene
  • Allyl acetate

Known Uses

Intermediate in the synthesis of 1,4-butanediol which is used in the synthesis of linear polyester resins. (Kirk-Othmer, 3rd ed)

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Short-Term Toxicity

  • 13 weeks (Gavage)  (C93010)  Report Complete 
    • TOX-48 (NIH Number: 06-4413)
      Comparative Toxicity Studies of Allyl Acetate (CASRN 591-87-7), Allyl Alcohol (CASRN 107-18-6) and Acrolein (CASRN 107-02-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0, 6, 12, 25, 50, OR 100 MG/KG M: 0, 8, 16, 32, 62.5, OR 125 MG/KG; 10 PER GROUP.

Genetic Toxicology

  • Micronucleus  (A10642)  Completed 
    • Mice: B6C3F1
    • Male Negative 
    • Female Weakly Positive 
  • Micronucleus  (A37278)  Completed 
    • Rats: Fischer 344
    • Male Negative 
  • Salmonella  (A45510)  Completed 
    •  Positive 
  • Salmonella  (A87523)  Completed 
    •  Positive 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.