National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m930081

Testing Status of Nicotine (compounds related to) - M930081

 

CASRN: 54-11-5

Formula: C10-H14-N2

Synonyms/Common Names

  • Pyridine, 3-((2S)-1-methyl-2-pyrrolidinyl)-

Known Uses

Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • C. elegans  (S0871)  Completed 
    • C. elegans
    • Dose: feed: (10, 12.6, 16, 20, 25, 32, 40, 50, 63, 79, 100 uM) 2/2/06 repro: (.5, .8, 1.25, 2, 3.14, 5, 8, 12, 5, 20, 31.4, 50 uM) 8/9/05 growth: (0, .1, .16, .25, .4, .63, 1, 2.5, 4, 6.3, 10) uM.

Genetic Toxicology

  • Salmonella  (A46915)  Completed 
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.