Testing Status of 2,3-Dichloropropene M940067

 

CASRN: 10061-02-6

Formula: C3-H4-Cl2

Synonyms/Common Names

  • 3-Dichloropropene, trans-

Known Uses

Preplant soil fumigant. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage; Intraperitoneal Injection)  (S0496)  Completed 
    • Citation: Medinsky MA, Bond JA, Dutcher JS, Birnbaum LS. Disposition of [14C]2,3-dichloropropene in Fischer-344 rats after oral or intraperitoneal administration. Toxicol Lett. 1984 Oct;23(1):119-25.Pubmed Abstract
    • Male Rats: F344/N
    • Dose: 32 MG/KG.
  • Absorption Disposition Metabolism Elimination (Inhalation)  (S0497)  Completed 
    • Citation: Bond JA, Medinsky MA, Dutcher JS, Henderson RF, Cheng YS, Mewhinney JA, Birnbaum LS. Disposition and metabolism of 2,3-[14C]dichloropropene in rats after inhalation. Toxicol Appl Pharmacol. 1985 Mar 30;78(1):47-54.Pubmed Abstract
    • Male Rats: F344/N
    • Dose: 7.5 PPM NOSE-ONLY.
  • Absorption Disposition Metabolism Elimination (Inhalation)  (S0498)  Completed 
    • Citation: Dutcher JS, Medinsky MA, Bond JA, Cheng YS, Snipes MB, Henderson RF, Birnbaum LS. Effect of vapor concentration on the disposition of inhaled 2,3-dichloropropene in Fischer-344 rats. Fundam Appl Toxicol. 1985 Oct;5(5):997-1005.Pubmed Abstract
    • Male Rats: F344/N
    • Dose: 0.4, 6 OR 40 PPM NOSE ONLY EXPOSURE FOR 6 HOURS.