National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m940096

Testing Status of Acetochlor - M940096

 

CASRN: 34256-82-1

Formula: C14-H20-Cl-N-O2

Synonyms/Common Names

  • Acetamide, 2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)- (9CI)
  • Harness (R)
  • Nevirex (R)
  • o-Acetotoluidide, 2-chloro-N-(ethoxymethyl)-6'-ethyl- (8CI)

Known Uses

Used as a selective pre-emergence, early post-emergence, or pre-plant herbicide used to control annual grasses, certain annual broad-leaved weeds. Currently (1992) registered only in Argentina, south Africa, the soviet union and Hungary.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 4 days (Gavage)  (C94096)  Completed 
    • Liver Targeted Testing study of Toxcast Chemicals
    • Rats: Harlan Sprague-Dawley
    • Dose: Male rats: 0, 250 mg/kg/day.

Genetic Toxicology

  • (G94096)  On Test 

    Organ Systems Toxicity

    • single exposure Total Reproductive Capacity (Intraperitoneal Injection)  (TRC99002)  Completed 
      • Female Mice: (SEC/E X C57BL/E)F1
      • Dose: 225 MG/KG.

    Toxicogenomics

    • 4 days Microarray Analysis (Gavage)  (T94096)  Completed 
      • Liver Targeted Testing study of Toxcast Chemicals
      • Rats: Harlan Sprague-Dawley
      • Dose: 250 mg/kg; 6 rats.
    NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.