National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m940103

Testing Status of Sodium bromate - M940103

 

CASRN: 7789-38-0

Formula: Br-H-O3.Na

Synonyms/Common Names

  • Bromic acid, sodium salt

Known Uses

Analytical reagent, water disinfection by-product

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Toxicokinetic Study (Gavage; Topical Application)  (S0664)  Completed 
    • Citation: Sodium Bromate Preliminary Toxicokinetic Study Report. Bromide in Plasma of Male and Female FVB Mice Treated Dermally or via Drinking Water with Sodium Bromate for Two Weeks. July 14, 2000
    • Male and Female Mice: C57BL/6

Genetic Toxicology

  • Micronucleus  (A01583)  Completed 
    • Mice: P53 +/- (C57BL/6)
    • Male Positive 
    • Female Positive 
  • Micronucleus  (A47624)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Male Positive 
    • Female Positive 
  • Micronucleus  (A94113)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Male Positive 
    • Female Positive 

Organ Systems Toxicity

  • 14 weeks Continuous Breeding (Dosed-Water)  (RACB95004)  Completed 
    • Male and Female Rats: Sprague Dawley
    • Dose: 0, 35, 110, OR 350 MG/KG.
  • 28 days Repro/Dev Gen Tox (28-Day) (Dosed-Water)  (RDGT94007)  Completed 
    • Citation: Final Report on Sodium Bromate: Short Term Reproductive and Developmental Toxicity Study When Administered to Sprague-Dawley Rats in the Drinking Water
    • Male and Female Rats: Sprague Dawley
    • Dose: TASK 1: 0, 250, 500, 1000, OR 2000 PPM TASK 2: 0, 25, 80, OR 25O PPM.
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