National Toxicology Program

National Toxicology Program

Testing Status of Hexachloroacetone - M940104


CASRN: 116-16-5

Formula: C3-Cl6-O

Synonyms/Common Names

  • Bis(trichloromethyl) ketone
  • HCA
  • Hexachloropropanone
  • Hexachloro-2-propanone
  • 1,1,1,3,3,3-Hexachloro-2-propanone (9CI)

Known Uses

Desiccant, herbicide

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • 35 days Repro/Dev Gen Tox (28-Day) (Dosed-Water)  (RDGT94008)  Completed 
    • Citation: Short-Term Reproductive and Developmental Toxicity of Hexachloroacetone (CAS #116-16-5) Administered in Drinking Water to Sprague-Dawley Rats.
    • Male and Female Rats: Sprague Dawley
    • Dose: RANGE FINDING: 0, 39, 156, 625, OR 2500 PPM MAIN: 0, 25, 100, OR 400 PPM.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.