National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m950052

Testing Status of Vincristine sulfate salt - M950052

 

CASRN: 2068-78-2

Formula: C46-H56-N4-O10.H2-O4-S

Synonyms/Common Names

  • Leurocristine sulfate (1:1)
  • Vincaleukoblastine, 22-oxo-, sulfate (1:1) (salt) (9CI)

Known Uses

Chemotherapeutic agent (antineoplastic drug). Antitumor alkaloid isolated from Vinca Rosea. (Merck, 11th ed.)

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Comet Assay  (G04864B)  Completed 
    • Rats
  • (F10511)  Completed 
    • (F69492)  Completed 
      • Micronucleus  (G04864)  Completed 
        • Rats: Wistar Han
        • Male Negative 
      NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.