National Toxicology Program

National Toxicology Program

Testing Status of Transgenic model evaluation (N-Methylolacrylamide) - M950083


CASRN: 924-42-5

Formula: C4-H7-N-O2

Synonyms/Common Names

  • N-methololacrylamide (Transgenic model evaluation)
  • N-(Hydroxymethyl)-acrylamide (8CI)
  • N-(Hydroxymethyl)-2-propenamide (9CI)

Known Uses

Proposed for use in sunscreen preps. Polymers for coating, varnishes, adhesives, crease-proof & wrinkle-resistant fabrics, perm-press textiles by irradiation bonding.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 24 weeks (Gavage)  (C95007G)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: 0 OR 50 MG/KG; 15/SEX/DOSE -- 5 TIMES PER WEEK.
  • 24 weeks (Topical Application)  (C95007H)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: 0 OR 50 MG/KG; 15 (30 CONTROLS)/SEX/DOSE -- 5 TIMES PER WEEK.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.