National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m950084

Testing Status of Transgenic model evaluation (Resorcinol) - M950084

 

CASRN: 108-46-3

Formula: C6-H6-O2

Synonyms/Common Names

  • 1,3-Benezenediol (9CI)
  • Resorcinol (Transgenic model evaluation)

Known Uses

Tanning, chemical production, dyes, cosmetics, pharmaceuticals, photography, intermediate. The objective of this study is to evaluate the Tg.AC and p53+/- transgenic mice models to identify chemicals for carcinogenic potential.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 24 weeks (Topical Application)  (C95007I)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: 0 OR 225 MG/KG; 15 (30 CONTROLS)/SEX/DOSE -- 5 TIMES PER WEEK.
  • 24 weeks (Gavage)  (C95007J)  Completed 
    • Mice: P53 +/- (C57BL/6)
    • Dose: 0 OR 225 MG/KG; 15/SEX/DOSE -- 5 TIMES PER WEEK.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.