National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m950088

Testing Status of Transgenic model evaluation (p-Anisidine HCl) - M950088

 

CASRN: 20265-97-8

Formula: C7-H9-N-O.Cl-H

Synonyms/Common Names

  • p-Anisidine hydrochloride Transgenic model evaluation
  • 4-Methoxybenzeneamine hydrochloride (9CI)

Known Uses

Manufacture of azo dyes. The objective of this study is to evaluate the Tg.AC and p53+/- transgenic mice models to identify chemicals for carcinogenic potential.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 24 weeks (Topical Application)  (C95007Q)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: 0 OR 133 MG/KG; 15/SEX/DOSE -- 5 TIMES PER WEEK.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.