National Toxicology Program

National Toxicology Program

Testing Status of 3,3,4,4,5-Pentachlorobiphenyl (PCB 126) - M950120


CASRN: 57465-28-8


Formula: C12-H5-Cl5

Synonyms/Common Names

  • 1,1'-Biphenyl, 3,3',4,4',5-pentachloro- (9CI)
  • PCB 126

Known Uses

Dielectric medium in transformers

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • GD 6 to PND 21 (Gavage)  (C95120)  Completed 
    • Tier One BDE TGMX Study
    • Rats: Wistar Han
    • Dose: 0, 10, 50, or 250 ng/kg; 10/group.

Special Studies

  • Toxicokinetic Study (Gavage)  (S0624)  Completed 
    • Citation: Amended Toxicokinetic Study Report. Single Gavage Administration Toxicokinetic Study of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) in Female Harlan Sprague-Dawley Rats. January 15, 2007
    • Male and Female Rats: Sprague Dawley

Genetic Toxicology

  • Salmonella  (G95120)  On Test 
    • Lot/Batch:  130494


  • Microarray Analysis (Gavage) Selected (T95120)  
    • Tier One BDE TGMX Study
    • Rats: Wistar Han
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.