Testing Status of Transgenic model evaluation (Methylphenidate hydrochloride) M950121

 

CASRN: 298-59-9

Formula: C14-H19-N-O2.Cl-H

Synonyms/Common Names

  • Methylphenidate hydrochloride (Transgenic model evaluation)
  • Ritalin hydrochloride (Transgenic model evaluation)

Known Uses

Central stimulant. The objective of this study is to evaluate the Tg.AC and p53+/- transgenic mice models to identify chemicals for carcinogenic potential.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 24 weeks (Dosed-Feed)  (C95007V)  Completed 
    • Mice: P53 +/- (C57BL/6); Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: 0, 50, 250, OR 500 PPM IN FEED.