National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m950127

Testing Status of Retinoid project 4 (4-(Hydroxyphenyl)retinamide) - M950127

 

CASRN: 65646-68-6

Related: SEE RETINOID PROJECT 1, 2, AND 3

Formula: C26-H33-N-O2

Synonyms/Common Names

  • 4-Hydroxyphenyl retinamide

Known Uses

Project combining various forms of vitamin A (retinoids) to examine their use in the prevention and intervention of breast cancer.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 26 weeks (Dosed-Feed)  (C93028E)  Completed 
    • Citation: Rao G, Ney E, Herbert R. Changes associated with delay of mammary cancer by retinoid analogues in transgenic mice bearing c-neu oncogene. Breast Cancer Research and Treatment 58:241-254. (2000)
    • Citation: Rao G, Ney E, Herbert R. Effect of retinoid analogues on mammary cancer in transgenic mice with c-neu breast cancer oncogene. Breast Cancer Research and Treatment 48:265-271. (1998)
    • Citation: Rao G, Ney E, Herbert R. Influence of Diet on Mammary Cancer in Transgenic Mice Bearing an Oncogene Expressed in Mammary Tissue.
    • Mice: MMTV/NEU (Tg.Nk)
    • Dose: 20 ANIMALS PER GROUP.
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