National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960018

Testing Status of Endocrine disruptor (Nonylphenol) - M960018

 

CASRN: 84852-15-3

Related: NONYLPHENOL (104-40-5 & 84852-15-3)

Formula: C15-H24-O

Synonyms/Common Names

  • Nonylphenol (Endocrine disruptor)
  • para-Nonylphenol
  • Phenol, 4-nonyl-, branched

Known Uses

Used extensively as non-ionic detergent surfactants in industrial applications.

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • Multigenerational Screen (Dosed-Feed)  (MG96003)  Completed 
    • Male and Female Rats: Sprague Dawley (NCTR)
    • Reproductive Dose Range Finding (On Test)
      • Days of Treatment: 28 days
      • Dose: 0, 5, 25, 200, 500, 1000, or 2000 ppm
    • Immunotoxicity (On Test)
      • Days of Treatment: 4 weeks
      • Dose: 0, 25, 500, or 2000 ppm
    • Behavioral Toxicity (On Test)
      • Days of Treatment: 10 weeks
      • Dose: 0, 25, 500, or 2000 ppm
    • Multigeneration Reproductive Study (F0) (On Test)
      • Days of Treatment: 20 weeks
    • Multigeneration Reproductive Study (F1) (On Test)
      • Days of Treatment: 20 weeks
    • Multigeneration Reproductive Study (F2) (On Test)
      • Days of Treatment: 20 weeks
    • Multigeneration Reproductive Study (F3) (On Test)
      • Days of Treatment: 20 weeks
    • Multigeneration Reproductive Study (F4) (On Test)
      • Days of Treatment: 20 weeks
    • Cancer Study (F1) (Cancelled)
      • Cancer Study (F3) (Cancelled)
      NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.