National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960019

Testing Status of Vinclozolin - M960019

 

CASRN: 50471-44-8

Related: ENDOCRINE DISRUPTER

Formula: C12-H9-Cl2-NO3

Synonyms/Common Names

  • 2,4-Oxazolidinedione, 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-
  • Vorlan

Known Uses

Fungicide, bactericide, wood preservative; used on fruits, vegetables, ornamental plants and vines. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 4 days (Gavage)  (C96019B)  Completed 
    • Liver Targeted Testing study of Toxcast Chemicals
    • Rats: Harlan Sprague-Dawley
    • Dose: Male rats: 0, 221 mg/kg/day.

Organ Systems Toxicity

  • 9 months Continuous Breeding (Gavage)  (R08012)  Completed 
    • Rats: Wistar Han

Toxicogenomics

  • 4 days Microarray Analysis (Gavage)  (T96019)  Completed 
    • Liver Targeted Testing study of Toxcast Chemicals
    • Rats: Harlan Sprague-Dawley
    • Dose: not provided; 6 rats.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.