National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960021

Testing Status of Genistein - M960021

 

CASRN: 446-72-0

Related: ENDOCRINE DISRUPTER

Formula: C15-H10-O5

Synonyms/Common Names

  • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)- (9CI)

Known Uses

Antineoplastic agent; growth inhibitor; naturally-occurring phytoestrogen found in several plants including soy products. Nutritional and pharmaceutical applications. Chemical probe to explore signal transduction pathways

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (A90231)  Completed 
    •  Positive 

Organ Systems Toxicity

  • 180 days Immunotoxicity (Gavage)  (IMM20705)  Completed 
    • Female Mice: NOD/MrKTac
    • Dose: Naive, 0, 2, 6, or 20 mg/kg/day.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.