Testing Status of Leucomalachite green M960026
CASRN: 129-73-7
Related: MALACHITE GREEN CHLORIDE
Formula: C23-H26-N2
Synonyms/Common Names
- Benzenamine, 4,4'-phenylmethylene)Bis(N,N-dimethyl- (9CI)
- Malachite green leuco
- Tetramethyldiaminotriphenylmethane
Known Uses
Plant fungicide; staining bacteria; antiseptic; dyeing textiles
Chemical Properties
Toxicity Effects (HSDB)
Short-Term Toxicity
- 28 days (Dosed-Feed)
(C93029B)
Report Complete
- Rats: F344/N; Mice: B6C3F1/NCTR BR (C57BL/6N x C3H/HEN MTV-)
- 4 weeks (Dosed-Feed)
(C93029)
Completed
- Rats: F344/N; Mice: B6C3F1/NCTR BR (C57BL/6N x C3H/HEN MTV-)
- Dose: 0, 96, 290, 580, OR 1160 PPM.
Long-Term Carcinogenicity
- 2 years (Dosed-Feed)
(C93029)
Report Complete
- TR-527 (NIH Number: 05-4463)
(Peer Review Approval 02/17/2004A )
Toxicology and Carcinogenesis Studies of Malachite Green Chloride and Leucomalachite Green (CASRNs 569-64-2 and 129-73-7) in F344/N Rats and B6C3F1 Mice (Feed Studies) - Rats: F344/N; Mice: B6C3F1/NCTR BR (C57BL/6N x C3H/HEN MTV-)
- Carcinogenesis Results
- Male Rats Equivocal Evidence
- Female Rats Equivocal Evidence
- Female Mice Some Evidence
- Dose: R: 0, 91, 272, OR 543 PPM M: 0, 91, 204, OR 408 PPM.
- TR-527 (NIH Number: 05-4463)
(Peer Review Approval 02/17/2004A )
Genetic Toxicology
- Micronucleus
(A31156)
Completed
- Mice: B6C3F1
- Male NA
- Female Positive