National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960030

Testing Status of Patulin - M960030

 

CASRN: 149-29-1

Formula: C7-H6-O4

Synonyms/Common Names

  • Claviformin
  • 4,6-Dihydro-4-hydroxy-2H-furo(3,2-c)pyran-2-one
  • 2,4-Dihydroxy-3,4-lactone
  • Penicidin

Known Uses

An antibiotic derived from the metabolites of a number of fungi (Merck, 11th). A mycotoxin.

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage)  (IMM96010)  Completed 
    • Female Mice: B6C3F1
    • Mice Female Negative 
    • Dose: 0, 0.08, 0.16, 0.32, 0.64, 1.28, OR 2.56 MG/KG/DAY.
  • 28 days Immunotoxicity (Gavage)  (IMM96016)  Completed 
    • Female Rats: F344/N
    • Dose: 0, 1.28, 2.56, OR 5.12 MG/KG/DAY.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.