Testing Status of Transgenic model evaluation (Phenolphthalein) M960032

 

CASRN: 77-09-8

Formula: C20-H14-O4

Synonyms/Common Names

  • 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone (9CI)
  • Phenolphthalein (Transgenic model evaluation)

Known Uses

Laboratory reagent. Dyes. Cathartic drug in laxatives. the objective of this study is to evaluate the Tg.AC and p53+/- transgenic mice models to identify chemicals for carcinogenicity.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 26 weeks (Dosed-Feed)  (C55798C)  Completed 
    • Mice: P53 +/- (C57BL/6)
    • Dose: FEMALE MICE ONLY: 0, 200, 375, 750, 3000, OR 12000 PPM; 20/DOSE.