National Toxicology Program

National Toxicology Program

Testing Status of Toxic equivalency factor evaluation ((PCB 126) 3,3',4,4',5-pentachlorobiphenyl) - M960052


CASRN: 57465-28-8


Formula: C12-H5-Cl5

Synonyms/Common Names

  • 1,1'-Biphenyl, 3,3',4,4',5-pentachloro- (9CI)
  • PCB 126
  • PCB 126 (Toxic equivalency factor evaluation)
  • 3,3',4,4',5-Pentachlorobiphenyl (Toxic equivalency factor evaluation)

Known Uses

Dielectric medium in transformers

Chemical Properties

Toxicity Effects (HSDB)

Long-Term Carcinogenicity

  • 2 years (Gavage)  (C96007D)  Report Complete 
    • TR-520 (NIH Number: 06-4454)  (Peer Review Approval 02/17/2004A )
      Toxicology and Carcinogenesis Studies of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) in Female Harlan Sprague-Dawley Rats (Gavage Studies)
    • Rats: Harlan Sprague-Dawley
    • Carcinogenesis Results
      • Female Rats Clear Evidence 
    • Dose: FEMALE RATS ONLY: PCB-126 -- 0, 10, 30, 100, 175, 300, 550, OR 1000 NG/KG; 100/DOSE.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.