National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960059

Testing Status of Transgenic LECM (Pyridine) - M960059

 

CASRN: 110-86-1

Formula: C5-H5-N

Synonyms/Common Names

  • Azabenzene
  • Pyridine (Transgenic LECM)
  • Transgenic-Laboratory of Environmental Carcinogenesis and Mutagenesis (Pyridine)

Known Uses

Solvent, organic synthesis, flavoring ingredient, manufacture of fungicides, pharmaceuticals, dyestuff, explosives, manufacture of vitamins, sulfa drugs, intermediate in manufacture of diquat & paraquat, waterproofing textiles (HSDB 1990) -

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 26 weeks (Dosed-Water)  (C55301C)  Completed 
    • Mice: P53 +/- (C57BL/6)
    • Dose: MM: 0, 250, 500, OR 1000 PPM FM: 0, 125, 250, OR 500 PPM; 10/SEX/DOSE.
  • 20 weeks (Topical Application)  (C55301D)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: FM ONLY: 0, 1.5, 3.0, OR 6.0 MG/200 UL; 15/DOSE.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.