National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960065

Testing Status of Transgenic LECM (Pentachlorophenol) - M960065

 

CASRN: 87-86-5

Related: PENTACHLOROPHENOL

Formula: C6-H-Cl5-O

Synonyms/Common Names

  • Pentachlorophenol (Transgenic LECM)
  • Transgenic-Laboratory of Environmental Carcinogenesis and Mutagenesis (Pentachlorophenol)

Known Uses

Wood preservative; fungicide; soil fumigant for termites; preharvest defoliant; seed treatment for beans; preservative for paint, leather, textiles, inks; antibacterial agent in disinfectants & cleansers. Special LECM transgenic mouse study.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 26 weeks (Dosed-Feed)  (C89002B)  Completed 
    • Mice: P53 +/- (C57BL/6)
    • Dose: M&F: 0, 100, 200, OR 400 PPM; 10/SEX/DOSE.
  • 20 weeks (Topical Application)  (C89002C)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: FM ONLY: 0, 0.75, 1.5, OR 3.0 MG/200 UL; 15/DOSE.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.