National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960069

Testing Status of Acesulfame potassium - M960069

 

CASRN: 55589-62-3

Related: TRANSGENIC MODEL EVALUATION II (ACESULFAME POTASSIUM)

Synonyms/Common Names

  • Acesulfame K
  • 1,2,3-Oxathiazin-4(3H)-one, 6-methyl-, 2,2-dioxide, potassium salt
  • Potassium 6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide

Known Uses

Artificial sweetener

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Toxicokinetic Study (Gavage; Intravenous)  (S0799)  Completed 
    • Male and Female Mice: C57BL/6
    • Dose: feed: 0.1 - 5%, gavage: equivalent feed doses IV:tbd.

Genetic Toxicology

  • Micronucleus  (A81568)  Completed 
    • Mice: P53 +/- (C57BL/6)
    • Male Positive 
    • Female Negative 
  • Micronucleus  (A99134)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Male Negative 
    • Female Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.